@charset "UTF-8";

/*
日本薬物動態学会第41回年会つくば. CSS
Author: Kazuya Tahara(Hdj)
Version: 20251120
*/


/*-----------------------------------------------
 __ResetCss
-----------------------------------------------*/
html, body, div, span, applet, object, iframe,
h1, h2, h3, h4, h5, h6, p, blockquote, pre,
a, abbr, acronym, address, big, cite, code,
del, dfn, em, img, ins, kbd, q, s, samp,
small, strike, strong, sub, sup, tt, var,
b, u, i, center,
dl, dt, dd, ol, ul, li,
fieldset, form, label, legend,
table, caption, tbody, tfoot, thead, tr, th, td,
article, aside, canvas, details, embed,
figure, figcaption, footer, header, hgroup,
menu, nav, output, ruby, section, summary,
time, mark, audio, video {
margin: 0;
padding: 0;
border: 0;
font-style:normal;
font-weight: normal;
vertical-align: baseline;
box-sizing:border-box;
}

article, aside, details, figcaption, figure,
footer, header, hgroup, menu, nav, section {
display: block;
}

html{
overflow-y: scroll;
}

blockquote, q {
quotes: none;
}

blockquote:before, blockquote:after,
q:before, q:after {
content: '';
content: none;
}

input, textarea{
margin: 0;
padding: 0;
}

ol, ul{
list-style:none;
}

table{
border-collapse: collapse; 
border-spacing:0;
}
table td{
vertical-align:middle;
}
caption, th{
text-align: left;
}

strong *,
strong{
	font-weight:bold;
}

a:focus {
outline:none;
}

/*ClearFix*/
.clearfix:after {
content: "."; 
display: block;
clear: both;
height: 0;
visibility: hidden;
}

.clearfix {
min-height: 1px;
}

* html .clearfix {
height: 1px;
/*¥*//*/
height: auto;
overflow: hidden;
/**/
}
html{
font-size: 62.5%;
scroll-behavior: smooth;
}
/*-----------------------------------------------
 __BassSetting
-----------------------------------------------*/
body{
	color: #000;
  font-family: "Noto Sans JP", sans-serif;
  font-optical-sizing: auto;
  font-weight: 400;
  font-style: normal;
	line-height:1.6;
  background-color: #588dcc;
  -webkit-text-size-adjust: 100%;
  text-size-adjust: 100%;
}
body.En{
	font-family: "Noto Sans", sans-serif;
  font-optical-sizing: auto;
  font-weight: 400;
  font-style: normal;
  font-variation-settings:  "wdth" 100;
	line-height: 1.4;
}

a{
	color: #3399cc;
}
a:hover{
	color: #FFA000;
}
.Wrapper {
	display:flex;
	justify-content:space-between;
	flex-direction:row-reverse;
	width:1000px;
	margin:0 auto;
}
.Content{
    width: 760px;
    background-color: #FFF;
    background-image: url("refer/bg_header.png"), url("refer/bg_content.jpg");
    background-position: 100% 0, 0 0;
    background-repeat: no-repeat, no-repeat;
}

/*-----------------------------------------------
 __#HEADER
-----------------------------------------------*/
#HEADER{
	width:760px;
	height:150px;
	margin:0 auto;
	padding-top:50px;
}
.Low #HEADER{
	padding-top: 25px;
}
#HEADER h1{
	width:473px;
	height:74px;
	font-size:1px;
	text-indent:-9999px;
	margin:0 auto auto auto;
  background: url("refer/title_main.png") no-repeat 0 0;
	background-size:contain;
}
.Low #HEADER h1{
	width: 335px;
	height: 106px;
  background: url("refer/title_main_sub.png") no-repeat 0 0;
	background-size: contain;
}
#HEADER h1 a{
	display:block;
	width:100%;
	height:100%;
}
.En #HEADER{
	padding-top: 14px;
}
.En #HEADER h1{
	width:623px;
	height:124px;
	font-size:1px;
	text-indent:-9999px;
	margin:0 auto auto auto;
  background: url("refer/title_main_en.png") no-repeat 0 0;
	background-size:contain;
}

/*-----------------------------------------------
 __Nav
-----------------------------------------------*/
nav{
	width:240px;
	padding-top:40px;
    background: #002259;
    position: relative;
}
nav .Lang{
    width: 140px;
    height: 50px;
    color: rgba(0, 0, 0, 0.3);
    font-weight: 500;
    line-height: 65px;
    font-size: 1.6rem;
    text-align: center;
    background-color: #ffe003;
    border-radius: 0 0 8px 8px;
    position: absolute;
    left: 45px;
    top: -20px;
}
.En nav .Lang{
  font-family: "Noto Sans JP", sans-serif;
}
nav .Lang a{
    display: block;
    width: 100%;
    height: 100%;
    color: #000;
    font-weight: 500;
    text-decoration: none;
    border-radius: 0 0 8px 8px;
}
nav .Lang a:hover{
	background-color:rgba(255,255,255,0.4);
}
nav ul{
	display:flex;
	flex-direction:column;
	margin:0 auto 20px;
}
nav ul li{
	font-weight:400;
  font-size: 1.6rem;
	color: rgba(255,255,255,0.3);
	padding:7.5px 0 7.5px 30px;
	position: relative;
}
nav ul li::before{
	display: block;
	width: 8px;
	height: 5px;
	content: "";
	background: url(refer/ic_nav.png) no-repeat 0 0;
	background-size: contain;
	position: absolute;
	top: 18px;
	left: 10px;
	z-index: 10;
}
.En nav ul li::before{
	position: absolute;
	top: 16px;
	left: 10px;
}
nav ul li a{
	box-sizing: content-box;
	display:block;
	width:100%;
	height:100%;
	color:#FFF;
	text-decoration:none;
	padding:7.5px 0 7.5px 30px;
	margin:-7.5px 0 -7.5px -30px;
	position: relative;
	z-index: 1;
	overflow: hidden;
}
nav ul li a::before,
nav ul li a::after {
	background: #0047b9;
	content: '';
	position: absolute;
	z-index: -1;
	/*background-color: #f00;*/
	height: 100%;
	left: -180%;
	top: 0;
	transform: skew(80deg);
	transition-duration: 0.5s;
	transform-origin: top left;
	transition-timing-function: ease-in-out;
	width: 0;
}
nav ul li a:hover{
	color:#ffffff;
}
nav ul li a:hover:after {
	height: 100%;
	width: 300%;
}
nav .NavSC {
  width: 200px;
	color: rgba(0,0,0,0.30);
  font-size: 1.6rem;
  font-weight: 400;
	padding:5px 0 5px 15px;
  margin: 0 auto 40px;
  background-color: #ffe003;
	border-radius: 8px;
}	
nav .NavSC a{
	box-sizing: content-box;
	display:block;
	width:100%;
	height:100%;
	color: rgba(0,0,0,1.0);
	text-decoration:none;
	padding:5px 0 5px 15px;
	margin:-5px 0 -5px -15px;
	border-radius: 8px;
}
nav .NavSC a:hover{
	background-color:rgba(255,255,255,0.4);
}

/*-----------------------------------------------
 __Footer
-----------------------------------------------*/
footer{
	width:1000px;
	padding: 0.3em 0 1em;
	margin:-30px auto  auto;
}
footer .Copyright{
	font-size:1.2rem;
	text-align: right;
	padding-right: 50px;
}
footer .PageTop{
	/*scroll100px*/
	display:none;
	width:40px;
	height:40px;
	font-size:1px;
	text-indent:-9999px;
	position:fixed;
	bottom:50px;
	right:50px;
	background:#002259 url(refer/ic_pagetop.png) no-repeat 50% 50%;
	background-size:17px;
}
footer .PageTop a{
	display:block;
	width:100%;
	height:100%;
}
footer .PageTop a:hover{
	background:rgba(255,255,255,0.3);
}

/*-----------------------------------------------
 __Article
-----------------------------------------------*/
.Article {
	width:760px;
	min-height:950px;
	padding-top:40px;
	padding-bottom:50px;
	background: linear-gradient(180deg,rgba(255, 255, 255, 0.7) 0%, rgba(255, 255, 255, 1) 400px);
}
.Article h2{
	font-size:3rem;
  font-weight: 600;
	line-height:50px;
	margin:0 40px 40px 40px;
}
.Article h3{
	font-size:2.0rem;
	line-height: 1.1;
	font-weight: 600;
	margin:1.5em 40px 10px 40px;
	padding-left: 6px;
	border-left:4px solid #588dcc;
	position: relative;
}
.Article h2 + h3{
	margin-top:30px;
}
.Article h3:first-child{
	margin-top:30px;
}
.Article h4{
	font-size: 1.8rem;
	color: rgb(0, 65, 176);
	margin:2em 40px 5px 40px;
	font-weight:600;
}
.Article h3 + h4{
	margin-top:0;
}
.Article h5{
    font-size: 1.6rem;
	font-weight:bold;
	color:#333;
	margin:1em 40px 5px 40px;
}
.Article h6{
	margin:1em 40px 10px 40px;
}
.Article p{
    font-size: 1.6rem;
	margin:0 40px 1em 40px;
}
.Article ul{
    font-size: 1.6rem;
	margin:0 40px 1em 40px;
}
.Article ol{
    font-size: 1.6rem;
	margin:0 40px 1em 40px;
}
.Article ul ul,
.Article ul ol,
.Article ol ul,
.Article ol ol{
	font-size:100%;
}
.Article dl{
    font-size: 1.6rem;
	margin:0 40px 1em 40px;
}
.Article figure{
    font-size: 1.6rem;
	margin:0 40px 1em 40px;
	text-align:center;
}
.Article sup{
	font-size:1.2rem;
	vertical-align:top;
}
.Article sub{
	font-size:1.2rem;
	vertical-align:bottom;
}
.Article .Red{
	color:#F00;
}
.Article strong{
	font-weight:bold;
}
.Article table{
	width:auto;
    font-size: 1.6rem;
	margin:0 auto 1em 40px;
	border-top:1px solid #CCC;
	border-left:1px solid #CCC;
}
.Article table th{
	vertical-align:middle;
	padding:0.5em 1em;
	background:#EFEFEF;
	border-bottom:1px solid #CCC;
	border-right:1px solid #CCC;
}
.Article table td{
	vertical-align:middle;
	padding:0.5em 1em;
	background-color:#FFF;
	border-bottom:1px solid #CCC;
	border-right:1px solid #CCC;
}
.Article table th.Center,
.Article table td.Center{
	text-align:center;
}
.Article .UL{
	text-decoration:underline;
}
.Article .Flex{
	display:flex;
	justify-content:space-between;
}
.Article .ArignRight{
	text-align:right;
}
.Article .ArignCenter{
	text-align:center;
}
.Article .ListIc li{
	padding-left:1.2em;
	margin-bottom:0.5em;
	position:relative;
}
.Article .ListIc li::before{
	display:inline-block;
	width:16px;
	content:"●";
	font-size:10px;
	text-align:center;
	color: rgba(166,192,224,1.00);
	position:absolute;
	top:0.4em;
	left:0;
}
.Article .ListIc li .ListNum li{
    padding-left: 0;
}
.Article .ListIc li .ListNum li::before{
    display: none;
    content:"";
}
.Article .ListNote li{
	padding-left:1em;
	margin-bottom:0.5em;
}
.En .Article .ListNote li{
    padding-left: 0.7em;
}
.Article .ListNote li:before{
	display:inline-block;
	content:"※";
	color:#F00;
	text-indent:-1em;
}
.En .Article .ListNote li:before{
	display:inline-block;
	content:"*";
	color:#F00;
	text-indent:-0.7em;
}
.Article .ListNote li li{
	padding-left:0;
	margin-bottom:0;
}
.Article .ListNote li li:before{
	content:"";
	text-indent:0em;
}
.Article .ListNoteNum li{
	padding-left:1.5em;
	position: relative;
}
.Article .ListNoteNum li .Num{
	color:#F00;
	position: absolute;
	left:0;
	top:0;
}
.Article .ListNum li{
	margin-left:30px;
	margin-bottom:0.5em;
	list-style-type:decimal;
}
.Article .ListNum li ul,
.Article .ListNum li ol{
	margin:0;
}
.Article .ListNum li .ListNote li{
    text-indent: -1em;
	margin:0;
	padding-bottom:0;
	list-style-type:none;
}
.Article .ListLatin li{
	list-style-type: upper-latin;
}
.Article .ListNum li li{
	margin-left:0;
	list-style-type:none;
}
.Article  li ul,
.Article  li ol{
	margin-left:0;
	margin-right:0;
}
.Article  li .ListNote li:before{
	font-size: 1em;
	text-indent: 0;
	top: 0;
}
.Article .RevNote{
	margin:1em 10px 1em auto;
	padding:1em 0;
	border-top:1px solid #CCC;
}
.Article .FootInfo{
	padding-top:1em;
	margin-top:2em;
	border-top:2px solid #AC2026;
}
.Article .Bt{
	width:60%;
	line-height:1.6;
	text-align:center;
	font-weight:bold;
	color:#FFF;
	margin:0 auto 40px;
	border-radius:3px;
	background-color: rgba(0,87,175,1.00);
}
.Article .BtNoLink{
	padding-top:12px;
	padding-bottom:12px;
}
.Article .Bt a{
	display:block;
	width:100%;
	height:100%;
	color:#FFF;
	text-decoration:none;
	font-weight:bold;
	padding-top:12px;
	padding-bottom:12px;
	background-color:rgba(255,255,255,0.00);
}
.Article .Bt a:hover{
	display:block;
	background-color:rgba(255,255,255,0.2);
}
.Article .BtCoi{
	width:60%;
	background-image: url(refer/ic_note.png);
	background-repeat:no-repeat;
	background-position:20px 50%;
	background-size:20px;
}
.Article .BtSSL{
	width:60%;
	background-image: url(refer/ic_key.png);
	background-repeat:no-repeat;
	background-position:20px 50%;
	background-size:18px;
}
.Article .BtPdf{
	background-image: url(refer/ic_pdf.png);
	background-repeat:no-repeat;
	background-position:20px 50%;
	background-color:#C80F13;
	background-size:30px;
}
.Article .BtXls{
	background-image:url(refer/ic_xls.png);
	background-repeat:no-repeat;
	background-position:20px 50%;
	background-color: #3CA503;
	background-size:24px;
}
.Article .BtWord{
	background-image:url(refer/ic_word.png);
	background-repeat:no-repeat;
	background-position:20px 50%;
	background-color: rgba(0,147,187,1.00);
	background-size:24px;
}
.Article .BtPPT{
	background-image:url(refer/ic_ppt.png);
	background-repeat:no-repeat;
	background-position:20px 50%;
	background-color: rgba(255,144,0,1.00);
	background-size:24px;
}
.Article .BtLink{
	width:60%;
	background-image:
url(refer/ic_link_l.png),
url(refer/ic_link_r.png);
	background-repeat:
no-repeat,
no-repeat;
	background-position:
10% 50%,
90% 50%;
    background-size: 14px, 14px;
}

.Article .IcPDF{
	padding-left:24px;
	padding-top:4px;
	min-height:28px;
	background: url( "refer/ic_link_pdf.png") no-repeat 0 50%;
	background-size: 20px;
}
.Article .IcPPT{
	padding-left:36px;
	padding-top:4px;
	min-height:28px;
	background: url(refer/ic_link_ppt_l_dl.png) no-repeat 0 50%;
}
.Article .IcLinkBlank{
	display:inline-block;
	padding-left:16px;
	background:url(refer/ic_link_blank.png) no-repeat 0 50%;
	background-size:12px;
}

/*-----------------------------------------------
 __ArticleTop
-----------------------------------------------*/
.ArticleTop{
	width:760px;
}
.ArticleTop .MainVisual{
	height:514px;
	position:relative;
}
.ArticleTop .MainVisual h2{
	display:none;
}
.ArticleTop .MainVisual .Outline{
	width:701px;
	height:515px;
	background: url(refer/outline.png) no-repeat 0 0;
	background-size:contain;
	position:absolute;
	left:50px;
	top:0px;
}
.En .ArticleTop .MainVisual .Outline{
	width:733px;
	height:489px;
	background: url(refer/outline_en.png) no-repeat 0 0;
	background-size:contain;
	position:absolute;
	left:20px;
	top:20px;
}
.ArticleTop .MainVisual .Outline dt{
	font-size:1px;
	text-indent:-9999px;
}
.ArticleTop .MainVisual .Outline dd{
	font-size:1px;
	text-indent:-9999px;
}
.ArticleTop .ArignRight{
	text-align:right;	
}
.ArticleTop .NoteBox{
	padding:1.6em 1.6em 0;
	margin-bottom:1.6rem;
	border:2px solid #F00;
}
.ArticleTop .NoteBox h2,
.ArticleTop .NoteBox h3{
	font-size:2.0rem;
	font-weight:bold;
	margin-bottom:0.5em;
}
.ArticleTop .NoteBox p{
    font-size: 1.6rem;
	margin-bottom:1em;
}
.ArticleTop .NoteBox .ListNote{
	margin-bottom:1em;
}
.ArticleTop .NoteBox .ListNote li{
	font-size:100%;
	padding-left:1em;
	padding-bottom:0;
	text-indent:0;
	position: relative;
}
.ArticleTop .NoteBox .ListNote li::before{
	display:inline-block;
	width:1em;
	content:"※";
	color:#F00;
	position:absolute;
	left:0;
	top:0;
}
.ArticleTop  h2{
	font-size:2.0rem;
	font-weight: 600;
	margin-bottom: 0.3rem;
  color: #c1388a;
}
.ArticleTop .WhatsNew{
	padding:40px 50px 40px 50px;
}
.ArticleTop .WhatsNew ul{
	max-height:150px;
	overflow-y: auto;
}
.ArticleTop .WhatsNew li{
    font-size: 1.6rem;
	padding:0 0 0.4em 6em;
	margin-bottom:0.4em;
	border-bottom:1px solid #b7b7b7;
	position:relative;
}
.ArticleTop .WhatsNew li .Date{
	font-size: 1.4rem;
	position:absolute;
	top: 0.2rem;
	left:0.2em;
}
.ArticleTop .WhatsNew .InfoBox{
	padding:1em 1em 0;
	margin-bottom:1em;
	border:2px solid rgba(255,0,4,1.00);
}
.ArticleTop .WhatsNew .InfoBox h3{
	font-size:114%;
	font-weight:bold;
	text-align: center;
	margin-bottom:1em;
}
.ArticleTop .WhatsNew .InfoBox p{
	margin-bottom:1em;
}
.ArticleTop .OfficeBox{
	display:flex;
	justify-content:space-between;
	padding:0 50px 50px 50px;
}
.ArticleTop .OfficeBox p{
    font-size: 1.4rem;
}
.ArticleTop .OfficeBox p strong{
    font-size: 1.6rem;
}
.ArticleTop .ListNote li{
	font-size:75%;
	padding-left:1em;
	text-indent:-1em;
	padding-bottom:10px;
}
.ArticleTop .Red{
	color:#F00;
}
.ArticleTop .UL{
	text-decoration:underline;
}
/*-----------------------------------------------
 __Outline
-----------------------------------------------*/
.Outline .BlankLink{
	display: inline-block;
	width: 10rem;
	color: #FFF;
	font-size: 1.2rem;
	text-align: center;
	text-decoration: none;
	margin-left: 6px;
	margin-right: 6px;
	padding-top: 1px;
	padding-bottom: 1px;
	vertical-align: 1px;
	background-color: #0025ca;
	border-radius: 4px;
}
.Outline .BlankLink:hover{
	background-color: #2f52f0;
}
/*-----------------------------------------------
 __SC
-----------------------------------------------*/
.SC .BlankLink{
	display: inline-block;
	width: 10rem;
	color: #FFF;
	font-size: 1.2rem;
	text-align: center;
	text-decoration: none;
	margin-left: 6px;
	margin-right: 6px;
	padding-top: 1px;
	padding-bottom: 1px;
	vertical-align: 1px;
	background-color: #0025ca;
	border-radius: 4px;
}
.SC .BlankLink:hover{
	background-color: #2f52f0;
}
.SC .BtGreet{
	width: 40%;
}
.SC .SponsorPDF img{
	border: 1px solid #CCC;
}
.SC .SponsorPDF img:hover{
	border: 1px solid #FFA000;
}